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Authors
Affiliations
1 Department of Endocrinology, Dr. ALM Post Graduate Institute of Basic Medicai Sciences, Chennai 600113, IN
2 Institute Hospital, Biomedical Engineering Division, IIT Madras, Chennai 600 036, IN
Source
Journal of Endocrinology and Reproduction, Vol 7, No 1&2 (2003), Pagination: 40-41
Abstract
Osteoporosis is characterized by impairment of bone mass and deterioration of bone microscopic structure, resulting in increased bone fragility and susceptibility to fracture. Osteoporosis is considered as a postmenopausal woman's disease; however, recent studies indicate that the effects of this disease in men are at least as severe as in women. Insulin-like growth factors (IGFs) and its binding proteins (IGFBPs) are known to influence the bone physiology.